
Real-World Impact with Digital Patient Twins
Explore real-world digital twins use-cases and how v-Patients streamline development, reduce risk, and bring products to market faster.

Tricuspid Valve Replacement Simulation
Simulating tricuspid valve replacement with virtual patients enabled a device team to analyze anatomical fit and function without a single animal trial.

Cardiac Catheter Design Optimization
A catheter concept and implantation strategy was refined through medical simulation on 3D patient anatomies, reducing design iterations and time-to-bench.

In-Silico Aortic Valve Bench Test
Digital twins enabled benchtop testing of an aortic valve concept in a fraction of the time, helping validate performance under real-world conditions.
Tricuspid Valve Replacement
CHALLENGE:
Tricuspid valve procedures are complex due to anatomical variability and limited imaging access during planning.
SOLUTION:
A medical device company used v-Patients to simulate virtual implantation of their valve in a broad set of digital patient anatomies. This enabled them to test anatomical fit, validate implantation strategies, and ensure compatibility across body types—without needing early animal or cadaver testing.
Improved procedural planning
Reduced reliance on trial-and-error
Enhanced confidence before first in-human studies
Cardiac Catheter Optimization
CHALLENGE:
Designing a catheter that fits diverse anatomies requires multiple design cycles and expensive testing.
SOLUTION:
Developers used Virtonomy’s platform to test and iterate catheter designs in a wide range of digital patient models. They analyzed navigation paths, tip positioning, and contact points to detect potential design flaws and optimize performance—long before building physical prototypes.
Reduced R&D time
Minimized costs
Ensured the catheter design could adapt across real-world anatomical variationR&D time
Aortic Valve In-Silico Benchtop
CHALLENGE:
Traditional bench testing is limited by model variability, high costs, and regulatory constraints.
SOLUTION:
Instead of relying solely on physical models, the team simulated their entire benchtop study using digital twin hearts. By mimicking hemodynamic conditions, they virtually assessed valve performance and durability across different patient anatomies.
Delivered preclinical evidence faster
Avoided variability from physical setups
Laid groundwork for regulatory in-silico trials

Ready to simulate your use-case?
Book a short demo to explore how v-Patients could fit into your product lifecycle and learn more about other digital twins use-cases.